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Figure 3 Future perspectives and challenges In future research, the primary focus should be on deciphering the precise molecular mechanisms underlying C

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For the purpose of this review, we will focus on the ACPA-positive subset of RA and divide the progression of RA process into several distinct stages

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Further microscopic research revealed that melanosome transport between cells requires a number of steps, including bidirectional long-range transfer to the apical surface on microtubules, transfer to actin filaments, irreversible short-range transfer by actin dynamics followed by binding to the cell membrane (130)